Cast (in credits order) verified as complete
| David Arquette | ...Deputy Dwight "Dewey" Riley |
| Neve Campbell | ...Sidney Prescott |
| Courteney Cox | ...Gale Weathers |
| Matthew Lillard | ...Stu Macher |
| Rose McGowan | ...Tatum Riley |
| Skeet Ulrich | ...Billy Loomis |
| Jamie Kennedy | ...Randy Meeks |
| W. Earl Brown | ...Kenny, the cameraman |
| Joseph Whipp | ...Sheriff Burke |
| Liev Shreiber | ...Cotton Weary |
| Drew Barrymore | ...Casey Becker |
| Roger L. Jackson | ...Phone Voice (voice)(as Roger Jackson) |
| Kevin Patrick Walls | ...Steven Orth |
| David Booth (II) | ...Casey's Father |
| Carla Hatley | ...Casey's Mother |
| Lawrence Hecht | ...Neil Prescott |
| Lois Saunders | ...Mrs. Tate |
| Lisa Beach | ...TV Reporter #1 |
| Tony Kilbert | ...TV Reporter #2 |
| C.W. Morgan | ...Hank Loomis |
| Lee McCain | ...Mrs. Riley (as Francis Lee McCain) |
| Troy Bishop | ...Expelled Teen #1 |
| Ryan Kennedy | ...Expelled Teen #2 |
| Leonora Scelfo | ...Cheerleader in Bathroom |
| Nancy Ann Ridder | ...Girl in Bathroom |
| Lisa Canning | ...Reporter with Mask |
| Bonnie Wood | ...Young Girl in Video Store |
| Aurora Draper | ...Party Teen #1 |
| Kenny Kwong | ...Party Teen #2 |
| Justin Sullivan | ...Teen on Couch |
| Kurtis Bedford | ...Bored Teen |
| Angela Miller | ... Girl on Couch |
rest of cast listed alphabetically
| Linda Blair | ...Obnoxious Reporter (uncredited) |
| Wes Craven | ...Fred, The Janitor (uncredited) |
| Priscilla Pointer | ...Maureen Prescott (uncredited) |
| Henry Winkler | ...Principal Himbry (uncredited) |