At one point, Kevin Williamson was considering just producing, but he is now the (sole) screenwriter as well. Previous writers who worked on the project were Sean Hood (Halloween: Resurrection) and Tony Gayton (Murder by Numbers, The Salton Sea). This project has been in development since 2000.
Early versions of the script apparently tackled the werewolf legend in a different way, following the exploits of a New York City serial killer who discovers that his lethal tendencies are due to his lycanthrope nature.
Source: Yahoo!